Semex’s Post

Last week, I had the opportunity to present my poster titled "Y-chromosomal haplotype diversity of R1b-M269 subhaplogroups in individuals from the central region of Portugal" at the 27th Annual Meeting of the Portuguese Society of Human Genetics, which was held at Instituto Superior Técnico in Lisbon. I would like to express my gratitude to the organization for organizing another edition filled with exceptional presentations and stimulating symposiums. #populationgenetics #Y-Chromossome #R1b-M269

I am grateful to participate in International BioIron Meeting 2023 in Darwin, Australia and to have a possibility to meet so many experts in the field of iron studies in biology and medicine. Today I had a great opportunity to present our work in poster session entitled "Targeting iron metabolism and ferroptosis as a potential therapeutic approach against chordoma" (P29) and "Study of the mechanism of absorption of Sucrosomial® iron" (P30). #bioiron2023 #unibs #brescia

A new marine ciliate, Apofrontonia jejuensis n. sp. (Protozoa, Ciliophora, Oligohymenophorea) from Jeju Island, South Korea, and an improved diagnosis of the genus Apofrontonia - Frontiers in Marine Science

Did you know about toxicology's ancient roots? 🗿 From the ancient Egyptians to the Greeks and Romans, the quest to understand the effects of substances on our health runs deep into ancient history. However, Paracelsus, a 16th-century Swiss physician, is the one hailed as the father of toxicology. A contemporary of none other than Leonardo Da Vinci, and also considered "the father of modern chemotherapy, he taught us that "the dose makes the poison," a principle that remains central to the field today. Are you fascinated by how ancient wisdom shapes modern science? Share your thoughts below! #ToxicologyTrivia #AncientRootsModernScience #ClarityLabsInsights

New paper by the lab of Tugce Aktas (m) with first authors Petar Glažar (l) and Ibrahim Avsar Ilik (r) in Nature! Transposable elements are mobile genetic elements that can relocate within the genome and disrupt the normal function of genes, but are at the same time a source of evolutionary diversity. The scientists have identified a novel pathway that keeps the activity of transposons in somatic cells in check after they have been transcribed. ➡ Read more: https://lnkd.in/eSD67SuC ➡ Original Publication: https://lnkd.in/eciqTDqA

✨ Welcome Dr. Ana Carolina Campana Nascimento, she is a visiting scholar coming from Universidade Federal de Viçosa in Brazil. She'll be working with Dr. Diego Jarquin. Their research project is entitled: "Quantile Mixed Model for Genome Wide Association Studies." The project objective is to add the information of the genomic similarities between individuals (kinship) into Quantile Mixed Model (QMM), which combines all the desired properties of the QR with the MLM methodology into the genomic association studies (GWAS). #IFASResearch #AIatUF #UFPlantbreeder #AIinAg #multiomics 🌱 🧬

Did you know about toxicology's ancient roots? 🗿 From the ancient Egyptians to the Greeks and Romans, the quest to understand the effects of substances on our health runs deep into ancient history. However, Paracelsus, a 16th-century Swiss physician, is the one hailed as the father of toxicology. A contemporary of none other than Leonardo Da Vinci, and also considered "the father of modern chemotherapy, he taught us that "the dose makes the poison," a principle that remains central to the field today. Are you fascinated by how ancient wisdom shapes modern science? Share your thoughts below! #ToxicologyTrivia #AncientRootsModernScience #ClarityLabsInsights

"Platelet-Derived Mitochondria Modulate the Bioenergetic Phenotype of Human Neutrophils" This short oral was presented during #TargetingMitochondria 2023 by: Marie-France N. Soucy, Université de Moncton, Canada #WorldMitochondriaSociety #TargetingMitochondria2023 #mitochondria 

The Mysteries of Psilocybe (Magic Mushrooms): A Journey into Phylogeny and Biosynthesis 🧬   Researchers from London, Mexico, and the U.S published a new paper in the Proceedings of the National Academy of Sciences USA. Key findings include the estimation that the stem lineage of Psilocybe emerged around 67 million years ago, with diversification occurring approximately 56 million years ago. Furthermore, when the researchers looked at the genes involved in creating psilocybin, they found that there are two different ways these genes were arranged within the cluster. This difference corresponds to a significant split or separation within the Psilocybe genus and could mean that there were two independent occasions where Psilocybe acquired the ability to synthesis psilocybin. #psychedelicscience #psychedelics https://lnkd.in/g59W5rH9

Tokyo Metropolitan University researchers delved into DNA repair through homologous recombination, where the RecA protein plays a crucial role in fixing double-stranded DNA breaks. RecA/Rad51 orthologues are vital for this process across all living organisms, catalyzing the formation of the D-loop—an essential recombination intermediate. The mechanism involves homology recognition between double-stranded (ds)DNA and single-stranded (ss)DNA, leading to a hybrid-duplex core. Contrary to some models, our findings suggest that dsDNA recognizes homologous ssDNA before strand separation. This unique approach has implications for stress-free homology-dependent functions both in vivo and in vitro. More reading Takehiko Shibata, Shukuko Ikawa, Wakana Iwasaki, Hiroyuki Sasanuma, Hisao Masai, Kouji Hirota, Homology recognition without double-stranded DNA-strand separation in D-loop formation by RecA, Nucleic Acids Research, 2024;, gkad1260, https://lnkd.in/g_Z3F29U #Minnebio #ProteinCommunity2023