Associate Scientist, In Vivo Research

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

Arrowhead is seeking a highly motivated Associate Scientist to join our growing In Vivo Pharmacology team within the Biology Department at our Madison site. The successful candidate will be joining a team dedicated to discovering, developing, and translating novel drug targets.

Responsibilities

• Perform in vivo studies and ex vivo analysis to facilitate drug discovery and development in various diseases
• May contribute to the establishment of new preclinical animal disease models
• Read and apply relevant scientific literature to projects
• Contribute to the review and drafting of SOPs and other relevant documents
• Maintain a high level of productivity in the lab and perform critical experiments
• Prepare and maintain detailed record keeping of study documents
• Mentor junior teammates on procedures, processes, and/or other areas as needed
  
  

Requirements:

• Bachelor Degree in Biology or related field and some experience with small animal handling in a research setting (i.e. test article administration and tissue collection) - OR - an Associate Degree in a related area and 7 years of experience.
• Excellent record keeping and attention to detail
• Experience in data analysis, graphing and making presentations
• Ability to work independently and to handle multiple projects and deadlines
• Demonstrated innovation, creativity and resilience in problem solving
• Excellent oral and written communication skills
• Self-motivated team player with the ability to thrive in a fast paced, multi-disciplinary, matrixed environment
  
  

Preferred:

• Preclinical disease model development in the context of drug discovery
• Experiences with animal dose administration and surgical procedures
  
  

Wisconsin pay range

$55,000—$65,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the US for a company.

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