This morning Cabaletta Bio reported positive initial clinical data from the Phase 1/2 RESET-Myositis™ and RESET-SLE™ trials of CABA-201. Read our press release on the News & Media section of our website and join our live investor conference call and webcast today at 8:00 a.m. EDT here: https://lnkd.in/eFsVhdxz #CART #celltherapy #myositis #SLE #autoimmune
Cabaletta Bio
Biotechnology Research
Philadelphia, Pennsylvania 11,011 followers
Engineered T cell therapies designed for the treatment of patients with autoimmune diseases
About us
Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on the discovery and development of engineered T cell therapies that have the potential to provide a deep and durable, perhaps curative, treatment for patients with autoimmune diseases. The CABA™ platform encompasses two strategies: the CARTA (chimeric antigen receptor T cells for autoimmunity) strategy, with CABA-201, a 4-1BB-containing fully human CD19-CAR T, as the lead product candidate being evaluated in systemic lupus erythematosus and myositis, and the CAART (chimeric autoantibody receptor T cells) strategy, with multiple clinical-stage candidates, including DSG3-CAART for mucosal pemphigus vulgaris and MuSK-CAART for MuSK myasthenia gravis. The expanding CABA™ platform is designed to develop potentially curative therapies that offer deep and durable responses for patients with a broad range of autoimmune diseases. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA.
- Website
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http://www.cabalettabio.com
External link for Cabaletta Bio
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Philadelphia, Pennsylvania
- Type
- Public Company
- Founded
- 2017
- Specialties
- cell therapy, biotech, immunology, autoimmune, and rheumatology
Locations
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Primary
2929 Arch St
Suite 600
Philadelphia, Pennsylvania 19104, US
Employees at Cabaletta Bio
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Jeff Hines
Talent Acquisition Business Partner | Change Agent | Results Oriented Strategist
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Vanessa Salazar
Life Sciences Executive | Corporate and Business Development | Team Leader | DEI Champion | Yoga Instructor
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Wayne Hull
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Patricia Monaghan
Senior Manager, Quality Specialist at Cabaletta Bio
Updates
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Cabaletta Bio's Phase 1/2 RESET-SSc trial is now recruiting individuals with systemic sclerosis. The study is evaluating the safety and efficacy of CABA-201, an investigational CD19-CAR T cell therapy. Systemic sclerosis is a rare autoimmune disease that can affect the skin and organs in the body such as the heart, lungs and kidneys. Learn more at the link below: https://lnkd.in/eUf5J3-Y #CART #celltherapy #autoimmune #scleroderma #SSc
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Cabaletta Bio reposted this
Join us at our Satellite Symposium on June 14th at 8:15am CEST at the #EULAR2024 Congress in Vienna, Austria. We will have presentations from Georg Schett, a pioneer of CAR T cell therapy for the treatment of autoimmune diseases, and Carl June, a pioneer of the first CAR T cell therapy approved in oncology, as well as David J. Chang, MD, MPH, FACR, our Chief Medical Officer, sharing our initial clinical data with CABA-201 in myositis and lupus. Look forward to seeing you there! #EULAR2024 #CART #celltherapy #autoimmune
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Join us at our Satellite Symposium on June 14th at 8:15am CEST at the #EULAR2024 Congress in Vienna, Austria. We will have presentations from Georg Schett, a pioneer of CAR T cell therapy for the treatment of autoimmune diseases, and Carl June, a pioneer of the first CAR T cell therapy approved in oncology, as well as David J. Chang, MD, MPH, FACR, our Chief Medical Officer, sharing our initial clinical data with CABA-201 in myositis and lupus. Look forward to seeing you there! #EULAR2024 #CART #celltherapy #autoimmune
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Cabaletta Bio's Phase 1/2 RESET-MG trial is now recruiting individuals with generalized myasthenia gravis. The study is evaluating the safety and efficacy of CABA-201, an investigational CD19-CAR T cell therapy. Myasthenia gravis is an autoimmune disease that results from antibodies that get in the way of signals between nerves and muscles, causing profound muscle weakness. Learn more at the link below: https://lnkd.in/ef9K3HW3 #CART #celltherapy #autoimmune #myastheniagravis #MG
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Cabaletta Bio was grateful to be recognized on Tuesday night as the Healthcare Innovator of the Year at the 2024 Enterprise Awards hosted by the Philadelphia Alliance for Capital and Technologies (PACT). The shared vision and teamwork of the Crew have facilitated and accelerated our ability to develop potentially curative engineered cell therapies for patients with autoimmune disease. It is a privilege to be able to serve patients, families, and providers with our Crew members as part of the ecosystem across the region advancing innovative solutions within healthcare #PACT #2024EnterpriseAwards #CART #celltherapy #autoimmunedisease
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Cabaletta Bio reposted this
Our publication describing the preclinical work for CABA-201, a fully human 4-1BBz anti-CD19 CART for refractory autoimmune diseases, was recently published in Molecular Therapy Methods and Clinical Development. https://lnkd.in/e7h9kt8a
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We are looking forward to the EULAR 2024 Congress in Vienna, Austria. Join us at our Satellite Symposium on Friday, June 14th at 8:15am CEST for an exclusive and interactive presentation from Georg Schett, a pioneer of CAR T cell therapy for the treatment of autoimmune diseases, Carl June, a pioneer of the first CAR T cell therapy approved in oncology, and David J. Chang, MD, MPH, FACR, our Chief Medical Officer who oversaw the development of the only 2 products approved for systemic lupus erythematosus in the United States in over 60 years. You can also find us during the conference at Booths S18 and S19 in Hall B. We look forward to seeing you there! #EULAR2024 #CART #celltherapy #autoimmune
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Cabaletta Bio reported no CRS or ICANS of any grade observed during the 28-day DLT observation window for either of the first patients dosed with CABA-201 in the RESET-Myositis™ and RESET-SLE™ trials. We are looking forward to presenting initial clinical data on those patients at a satellite symposium at the EULAR 2024 Congress in June. Read our Q1 2024 earnings press release here: https://lnkd.in/eTSPtw29 #CART #celltherapy #myositis #SLE #autoimmune
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Cabaletta Bio is attending the Myasthenia Gravis Foundation of America (MGFA) 2024 National Patient Conference in Tampa, FL! Come see us at booth 17 to learn more about Cabaletta Bio and our ongoing clinical trials. #Myastheniagravis #MGFA #MG